Concentration-dependent suppression of cytokine release by enoxaparin fractions.
- Madhur D. Shastri (698427)
- Niall Stewart (698428)
- James Horne (737086)
- Syed Tabish R. Zaidi (698430)
- Sukhwinder Singh Sohal (317561)
- Gregory M. Peterson (564167)
- Heinrich Korner (5663749)
- Nuri Gueven (134653)
- Rahul P. Patel (698431)
Publication date
June 2015
DOIAbstract
<p>Inhibition of cytokine release by 0 to 40 μg/ml of enoxaparin fractions 1 and 4. Cytokines [IL-4 <b>(A)</b>, IL-5 <b>(B)</b>, IL-13 <b>(C)</b> and TNF- α <b>(D)</b>] were released by PBMCs of allergic asthmatic subjects (n = 5) after <i>ex-vivo</i> stimulation with PHA. Data is presented as percentage of PHA-stimulated control. *<i>p</i><0.05, **<i>p</i><0.01 and ***<i>p</i><0.001 versus PHA-stimulated control.</p
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