Gene expression analysis of laser-captured plaque CD68+ cells of non-diabetic <i>Ldlr</i>^<i>-/-</i> and STZ-diabetic <i>Ldlr</i>^<i>-/-</i> mice.

<p>CD68+ cells from aortic roots were isolated using LCM. mRNA was then isolated and subjected to analyses by RT-PCR. The results are from 3 independent samples, each representing amplified cDNA originating from the macrophages from one animal. mRNA levels are presented as relative levels compared to the non-diabetic baseline group. BL = baseline, chow = chow only, 0 = HDAd-0, LDLR = HDAd-LDL. * p<0.05 vs. respective non-diabetic group (Student’s t test); # p<0.05 as labeled (one-way ANOVA).