α-ANDV IgY/IgYΔFc administered after the onset of viremia does not protect hamsters from lethal HPS.

<p><b>A.</b> Survival curve of hamsters that were challenged with 200 PFU i.m. of ANDV on day 0 and passively transferred with 40,000 NAU/kg α-ANDV IgY/IgYΔFc, 40,000 NAU/kg α-ANDV human FFP, normal IgY, or normal FFP on days 8 and 10 post-infection (grey arrows). n = 8 for all groups. <b>B.</b> Serum and lung isolated from ANDV-infected hamsters on day 10 were evaluated for viral genome by RT-PCR. Symbols represent lung tissue titers from different animals. The mean for each group is also shown (line).