Examples of emphysema in the explanted lungs (H&E stained slides, magnification 200x).

<p>A-E: Emphysematous changes in patients with CF. A = score 1: some emphysematous changes are present next to a scar in <20% of residual lung tissue. B-D = score 2: emphysematous changes in 20–50% of residual lung tissue, next to scar tissue (B) or in the paraseptal region (C and D). E = Score 3: emphysematous changes in >50% of residual lung tissue. F = Emphysema in an explanted lung of a patient with severe COPD, for comparison.