Expressions of MMPs and S100As in eye challenged with <i>S</i>. <i>aureus</i> and its virulence factors.

<p>Eyes of C57BL/6 mice (4–6 per group) were inoculated intravitreally with live <i>S</i>. <i>aureus</i> (5000 CFU/eye), HKSA (5X10⁵ CFU/eye), LTA (0.1μg/eye), PGN (0.1μg/eye), TSST1 (0.1μg/eye), α-toxin (0.1μg/eye), SPA (0.1μg/eye), and PBS (2μl) for 24h. The mRNA expression of MMP2, MMP9, MMP13, S100A7, and S100A9 was determined by Real-time RT-PCR. Statistical analysis was performed by using one way ANOVA with Dunnett’s multi-comparison test. <i>*p</i> <0.05, <i>**p</i> <0.005.