<p>Mice were daily submitted to restraint stress and treated with L-tryptophan (Trp) or vehicle until euthanasia. Two days after the beginning of the stress protocol, two full-thickness excisional lesions (8-mm diameter) were made on the dorsal skin. Five days after wounding, lesions were lysated and the protein levels of tumor necrosis factor-α (TNF-α) (A) were measured by ELISA assay. The protein levels of indoleamine 2,3-dioxygenase (IDO) (45KDa) (B) were measured by immunoblotting. The expression of the IDO (B) was also detected in murine skin fibroblast culture. To observe the SR-7 expression on normal skin and wound area, immunohistochemistry for SR-7 (C) was performed in paraffin-embedded section of normal skin and wound area at 5 da...
The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter s...
The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter s...
The eosinophilia-myalgia syndrome (EMS) has been asso-ciated with ingestion of L-tryptophan (L-TRP) ...
<p>Mice were daily submitted to restraint stress and treated with L-tryptophan (Trp) or vehicle unti...
<p>Mice were daily submitted to restraint stress and treated with L-tryptophan (Trp) or vehicle unti...
It is increasingly recognized that psychological stress influences inflammatory responses and mood. ...
Acute tryptophan depletion is extensively used to investigate the implication of serotonin in the on...
Tryptophan metabolism has immunomodulatory ability and is considered to be an immunosuppressive path...
<div><p>Acute tryptophan depletion (ATD) is a method of lowering brain serotonin (5-HT). Administrat...
Background Tryptophan catabolites suppress immunity. Therefore, blocking tryptophan catabolism with ...
Tryptophan (TRP), which plays an important role in immune system regulation, protein synthesis, sero...
Several types of stress can increase vulnerability to developing depression. This depression may be ...
(A) Representative histograms showing the proliferation of αCD3/CD28-activated CFSE-labelled CD4+ T-...
Indoleamine 2,3-dioxygenase (IDO) has been identified as an important antimicrobial and immunoregula...
Previous studies in rats and humans have shown that the essential amino acid tryptophan (TRP) is dep...
The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter s...
The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter s...
The eosinophilia-myalgia syndrome (EMS) has been asso-ciated with ingestion of L-tryptophan (L-TRP) ...
<p>Mice were daily submitted to restraint stress and treated with L-tryptophan (Trp) or vehicle unti...
<p>Mice were daily submitted to restraint stress and treated with L-tryptophan (Trp) or vehicle unti...
It is increasingly recognized that psychological stress influences inflammatory responses and mood. ...
Acute tryptophan depletion is extensively used to investigate the implication of serotonin in the on...
Tryptophan metabolism has immunomodulatory ability and is considered to be an immunosuppressive path...
<div><p>Acute tryptophan depletion (ATD) is a method of lowering brain serotonin (5-HT). Administrat...
Background Tryptophan catabolites suppress immunity. Therefore, blocking tryptophan catabolism with ...
Tryptophan (TRP), which plays an important role in immune system regulation, protein synthesis, sero...
Several types of stress can increase vulnerability to developing depression. This depression may be ...
(A) Representative histograms showing the proliferation of αCD3/CD28-activated CFSE-labelled CD4+ T-...
Indoleamine 2,3-dioxygenase (IDO) has been identified as an important antimicrobial and immunoregula...
Previous studies in rats and humans have shown that the essential amino acid tryptophan (TRP) is dep...
The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter s...
The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter s...
The eosinophilia-myalgia syndrome (EMS) has been asso-ciated with ingestion of L-tryptophan (L-TRP) ...