<p>Comparison between expected numbers of induced DSB and hit domains as function of the dose; the calculations were performed assuming the standard input parameters of 30 DSB per Gy and cell nucleus and of 3000 domains (2 Mbp/domain).</p
<div><p>We present here an analysis of DSB induction and processing after irradiation with X-rays in...
<p>Solid lines labeled ‘F’ and ‘N’ were computed from Eq. (82) of <a href="http://www.plosone.org/ar...
We here propose a new model assembly for estimating the surviving fraction of cells irradiated with ...
<p>Normalized γH2AX dose response curve for AGD (full squares) and CHO (open squares) cells, and cor...
In developing mechanistic PK–PD models, incidence of toxic responses in a population has to be descr...
<p>Panel A: experimental data of flow cytometry measurements after irradiation with different X-rays...
Our rationale was to build a refined dosimetry model for 177Lu-DOTATATE in vivo experiments enabling...
Treatment response assays are often summarized by sigmoidal functions comparing cell survival at a s...
We present here an analysis of DSB induction and processing after irradiation with X-rays in an exte...
International audienceThe aim of this study is to build a simulation framework to evaluate the numbe...
(A) Model simulations of caspase-3 activation depending on the CD95L stimulation dose. Means and sta...
<p>(A) Dose response curves of MB and derivative against glutamate-induced neurotoxicity measured by...
Dose-response assays are a common and increasingly high throughput method of assessing the toxicity ...
<p>Dose-response coefficients obtained for the different adjustments to the models and their goodnes...
We present here an analysis of DSB induction and processing after irradiation with X-rays in an exte...
<div><p>We present here an analysis of DSB induction and processing after irradiation with X-rays in...
<p>Solid lines labeled ‘F’ and ‘N’ were computed from Eq. (82) of <a href="http://www.plosone.org/ar...
We here propose a new model assembly for estimating the surviving fraction of cells irradiated with ...
<p>Normalized γH2AX dose response curve for AGD (full squares) and CHO (open squares) cells, and cor...
In developing mechanistic PK–PD models, incidence of toxic responses in a population has to be descr...
<p>Panel A: experimental data of flow cytometry measurements after irradiation with different X-rays...
Our rationale was to build a refined dosimetry model for 177Lu-DOTATATE in vivo experiments enabling...
Treatment response assays are often summarized by sigmoidal functions comparing cell survival at a s...
We present here an analysis of DSB induction and processing after irradiation with X-rays in an exte...
International audienceThe aim of this study is to build a simulation framework to evaluate the numbe...
(A) Model simulations of caspase-3 activation depending on the CD95L stimulation dose. Means and sta...
<p>(A) Dose response curves of MB and derivative against glutamate-induced neurotoxicity measured by...
Dose-response assays are a common and increasingly high throughput method of assessing the toxicity ...
<p>Dose-response coefficients obtained for the different adjustments to the models and their goodnes...
We present here an analysis of DSB induction and processing after irradiation with X-rays in an exte...
<div><p>We present here an analysis of DSB induction and processing after irradiation with X-rays in...
<p>Solid lines labeled ‘F’ and ‘N’ were computed from Eq. (82) of <a href="http://www.plosone.org/ar...
We here propose a new model assembly for estimating the surviving fraction of cells irradiated with ...