<p>Reagents and conditions: (a) 2-phenylethanol for 9a, 3-phenyl-1-propanol for 9b, 110 <sup>o</sup>C; (b) NH<sub>4</sub>OH, H<sub>2</sub>O, Et<sub>2</sub>O, pH 8–10; (c) paraformaldehyde, pyrrolidine, EtOH, reflux.</p
<p>Reagents and Conditions: (a) Ethyl 3-bromobutyrate, Cs<sub>2</sub>CO<sub>3</sub>, MeCN, reflux, 2...
<p>Synthesis of 14: Reagents and conditions: (a) 4-phenyl butyl bromide, K<sub>2</sub>CO<sub>3</sub>...
<p>Reagents and Conditions; a. TBSCl, imidazole, CH<sub>2</sub>Cl<sub>2</sub>, rt, 1 h, 93%. b. acet...
<p>Reagents and conditions: (a) R<sup>2</sup>CH<sub>2</sub>OH, NaH, THF, reflux; (b) R<sup>2</sup>CH...
Reagents and conditions: a) N-hydroxyphthalimide, PPh3, DIAD, THF, 63%; b) TFA, CH2Cl2, 94%; c) TrSC...
<p>Reagents and conditions: (a) benzyl alcohol, 110 <sup>o</sup>C; (b) NH<sub>4</sub>OH, H<sub>2</su...
<p>Reagents and conditions: (a) conc. HCl, ZnCl<sub>2</sub>, HCHO(37% in H<sub>2</sub>O); (b) substi...
<p>Reagents and conditions: (a) benzyl mercaptan for <b>11a</b>, N-Benzylmethylamine for <b>11b</b>,...
Reagents and conditions: a) for 2a-c: HCl·H2NO(CH2)nCOOH, acetic acid, 80 °C, 3h; for 2d: HCl·H2NO(C...
<p>Reagents and conditions: (i) malonic acid (for compound 1), fumaric acid (for compound 2), adipic...
<p>Reagents and Conditions: i) EtOH, 40% NaOH, 0°C, stir, 30 min; rt, stir, 4 h; ii) EtOH, Phenylhyd...
<p>Reagents and conditions: i) (i) <i>S</i>-α-methylbenzylamine, EtOH, reflux, 2 days; (ii) H<sub>2<...
<p>Reagents and conditions: a. NaBH<sub>4</sub>, MeOH; b. PBr<sub>3</sub>, pyridine, 0°C; c. P(OEt)<...
1-Aryl-3-phenethylamino-1-propanone hydrochlorides 1-10, which are potentialpotent cytotoxic agents,...
<p><i>Reagent</i>s: <b>i</b>: NH<sub>2</sub>NH<sub>2</sub><sup>.</sup>H<sub>2</sub>O, EtOH, reflux, ...
<p>Reagents and Conditions: (a) Ethyl 3-bromobutyrate, Cs<sub>2</sub>CO<sub>3</sub>, MeCN, reflux, 2...
<p>Synthesis of 14: Reagents and conditions: (a) 4-phenyl butyl bromide, K<sub>2</sub>CO<sub>3</sub>...
<p>Reagents and Conditions; a. TBSCl, imidazole, CH<sub>2</sub>Cl<sub>2</sub>, rt, 1 h, 93%. b. acet...
<p>Reagents and conditions: (a) R<sup>2</sup>CH<sub>2</sub>OH, NaH, THF, reflux; (b) R<sup>2</sup>CH...
Reagents and conditions: a) N-hydroxyphthalimide, PPh3, DIAD, THF, 63%; b) TFA, CH2Cl2, 94%; c) TrSC...
<p>Reagents and conditions: (a) benzyl alcohol, 110 <sup>o</sup>C; (b) NH<sub>4</sub>OH, H<sub>2</su...
<p>Reagents and conditions: (a) conc. HCl, ZnCl<sub>2</sub>, HCHO(37% in H<sub>2</sub>O); (b) substi...
<p>Reagents and conditions: (a) benzyl mercaptan for <b>11a</b>, N-Benzylmethylamine for <b>11b</b>,...
Reagents and conditions: a) for 2a-c: HCl·H2NO(CH2)nCOOH, acetic acid, 80 °C, 3h; for 2d: HCl·H2NO(C...
<p>Reagents and conditions: (i) malonic acid (for compound 1), fumaric acid (for compound 2), adipic...
<p>Reagents and Conditions: i) EtOH, 40% NaOH, 0°C, stir, 30 min; rt, stir, 4 h; ii) EtOH, Phenylhyd...
<p>Reagents and conditions: i) (i) <i>S</i>-α-methylbenzylamine, EtOH, reflux, 2 days; (ii) H<sub>2<...
<p>Reagents and conditions: a. NaBH<sub>4</sub>, MeOH; b. PBr<sub>3</sub>, pyridine, 0°C; c. P(OEt)<...
1-Aryl-3-phenethylamino-1-propanone hydrochlorides 1-10, which are potentialpotent cytotoxic agents,...
<p><i>Reagent</i>s: <b>i</b>: NH<sub>2</sub>NH<sub>2</sub><sup>.</sup>H<sub>2</sub>O, EtOH, reflux, ...
<p>Reagents and Conditions: (a) Ethyl 3-bromobutyrate, Cs<sub>2</sub>CO<sub>3</sub>, MeCN, reflux, 2...
<p>Synthesis of 14: Reagents and conditions: (a) 4-phenyl butyl bromide, K<sub>2</sub>CO<sub>3</sub>...
<p>Reagents and Conditions; a. TBSCl, imidazole, CH<sub>2</sub>Cl<sub>2</sub>, rt, 1 h, 93%. b. acet...
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