<p>The continuous line = estimated effect of period; dashed lines = 95% confidence interval of the estimates.</p
<p>Lines represent estimates from the general linear model including effects of group, active day, a...
<p>The left line is the estimated age effect, the middle line refers to the estimated birth cohort e...
<p>Panels A and B exhibit the probability distribution plot of the standardized residuals, , for whi...
<p>The continuous line = estimated effect of cohort; dashed lines = 95% confidence interval of the e...
<p>The continuous line = estimated effect of age; dashed lines = 95% confidence interval of the esti...
<p>Parameter estimates of age, cohort and period effect from the full APC model for men (left) and w...
<p>Fig 3A represents the age-specific incidence rates, referred to the reference period 1975; Fig 3B...
<p>Fig 2A represents the age-specific incidence rates, referred to the reference period 1975; Fig 2B...
<p>The figure shows a cosine curve (green lines) with a 5-y periodicity and average estimates based ...
<p>The left line is the estimated age effect, the middle line refers to the estimated birth cohort e...
<p>Fig 5A represents the age-specific incidence rates, referred to the reference period 1975; Fig 5B...
Estimates of fixed-effect coefficients, with 95% confidence intervals, in the mixed-effects models.<...
<p>Mean and 95% confidence intervals of the single variable models, for each scenario (pre- and post...
<p>Coefficient estimates, standard errors, and 95% confidence interval for each coefficient in a mod...
Illustration of the longitudinal model for women only (Table 2, Model 1b, including 95% confidence i...
<p>Lines represent estimates from the general linear model including effects of group, active day, a...
<p>The left line is the estimated age effect, the middle line refers to the estimated birth cohort e...
<p>Panels A and B exhibit the probability distribution plot of the standardized residuals, , for whi...
<p>The continuous line = estimated effect of cohort; dashed lines = 95% confidence interval of the e...
<p>The continuous line = estimated effect of age; dashed lines = 95% confidence interval of the esti...
<p>Parameter estimates of age, cohort and period effect from the full APC model for men (left) and w...
<p>Fig 3A represents the age-specific incidence rates, referred to the reference period 1975; Fig 3B...
<p>Fig 2A represents the age-specific incidence rates, referred to the reference period 1975; Fig 2B...
<p>The figure shows a cosine curve (green lines) with a 5-y periodicity and average estimates based ...
<p>The left line is the estimated age effect, the middle line refers to the estimated birth cohort e...
<p>Fig 5A represents the age-specific incidence rates, referred to the reference period 1975; Fig 5B...
Estimates of fixed-effect coefficients, with 95% confidence intervals, in the mixed-effects models.<...
<p>Mean and 95% confidence intervals of the single variable models, for each scenario (pre- and post...
<p>Coefficient estimates, standard errors, and 95% confidence interval for each coefficient in a mod...
Illustration of the longitudinal model for women only (Table 2, Model 1b, including 95% confidence i...
<p>Lines represent estimates from the general linear model including effects of group, active day, a...
<p>The left line is the estimated age effect, the middle line refers to the estimated birth cohort e...
<p>Panels A and B exhibit the probability distribution plot of the standardized residuals, , for whi...