<p>Antibody staining on sections of P0 and P7 prostates with antibodies to CLU and TROP2 shows no accumulation of these proteins at earlier stages of development in controls (A, B, C, D). Increased expression of these markers is seen in the mutant (E, F, G, H) relative to controls from P7. Red arrowheads indicate buds.</p
Gene expression and functional studies have indicated that the molecular programmes in-volved in pro...
<div><p>(A) Ki-67 staining of AP lobe sections illustrates increasing proliferation with ...
<p>Expression of the PSC cell-specific markers <i>hhF4f-GFP</i> and Antp was assessed in lymph gland...
<p>Antibody staining of the luminal marker CK18 (green) on sections of P5 prostates show expression ...
<p>Antibody staining on sections of P7 (A), P10 (B) and adult (C) prostates demonstrate expression o...
<p>(A) Double immunofluorescence antibody staining of P10 mutant and control sections with Ki67 (gre...
<p>(A) A gene diagram of the alleles used to generate the <i>Pten</i> mutant animals with <i>R26R</i...
Gene expression and functional studies have indicated that the molecular programmes involved in pros...
<div><p>Gene expression and functional studies have indicated that the molecular programmes involved...
The PSA-Cre;Pten-loxP/loxP mouse prostate cancer model displays clearly defined stages of hyperplasi...
The PSA-Cre;Pten-loxP/loxP mouse prostate cancer model displays clearly defined stages of hyperplasi...
The PSA-Cre;Pten-loxP/loxP mouse prostate cancer model displays clearly defined stages of hyperplasi...
<p><b>A–I.</b> Cell proliferation was examined by immunostaining for Ki-67. Prostate sections isolat...
<p>(A) i) Heatmap demonstrating that control samples (C1-C5) show similar expression patterns to eac...
<p>(A) Immunostaining of dorsolateral prostate lobes of animals from the 56-week old group of differ...
Gene expression and functional studies have indicated that the molecular programmes in-volved in pro...
<div><p>(A) Ki-67 staining of AP lobe sections illustrates increasing proliferation with ...
<p>Expression of the PSC cell-specific markers <i>hhF4f-GFP</i> and Antp was assessed in lymph gland...
<p>Antibody staining of the luminal marker CK18 (green) on sections of P5 prostates show expression ...
<p>Antibody staining on sections of P7 (A), P10 (B) and adult (C) prostates demonstrate expression o...
<p>(A) Double immunofluorescence antibody staining of P10 mutant and control sections with Ki67 (gre...
<p>(A) A gene diagram of the alleles used to generate the <i>Pten</i> mutant animals with <i>R26R</i...
Gene expression and functional studies have indicated that the molecular programmes involved in pros...
<div><p>Gene expression and functional studies have indicated that the molecular programmes involved...
The PSA-Cre;Pten-loxP/loxP mouse prostate cancer model displays clearly defined stages of hyperplasi...
The PSA-Cre;Pten-loxP/loxP mouse prostate cancer model displays clearly defined stages of hyperplasi...
The PSA-Cre;Pten-loxP/loxP mouse prostate cancer model displays clearly defined stages of hyperplasi...
<p><b>A–I.</b> Cell proliferation was examined by immunostaining for Ki-67. Prostate sections isolat...
<p>(A) i) Heatmap demonstrating that control samples (C1-C5) show similar expression patterns to eac...
<p>(A) Immunostaining of dorsolateral prostate lobes of animals from the 56-week old group of differ...
Gene expression and functional studies have indicated that the molecular programmes in-volved in pro...
<div><p>(A) Ki-67 staining of AP lobe sections illustrates increasing proliferation with ...
<p>Expression of the PSC cell-specific markers <i>hhF4f-GFP</i> and Antp was assessed in lymph gland...