Chronic oral infection with <i>F</i>. <i>nucleatum</i> induced significant levels of serum <i>F</i>. <i>nucleatum</i>-specific antibodies.

<p>Graphs represent the fold-increase in <i>F</i>. <i>nucleatum</i>-specific IgG or IgM antibody titer in infected mice over control mice at both 12 and 24 weeks of infection. (*** <i>P</i><0.001).