<p>(A) and (B) respectively give the sample subthreshold and suprathreshold responses of each cell type to current ramp with <i>K</i> = 0.5μA/(cm<sup>2</sup>·ms) (blue), 1.5μA/(cm<sup>2</sup>·ms) (pink) and 5.0μA/(cm<sup>2</sup>·ms) (cyan blue). (C) and (D) respectively describe the separatrix (i.e., threshold) of two types of excitability on phase plane. The right panel in (C) is the enlarged view of the yellow region in its left panel. The separatrix of Type I neuron lies on the left side of Type II, which corresponds to a hyperpolarized spike threshold. As ramp slope <i>K</i> changes, the variable <i>w</i> in Type II neuron varies in a much larger scale compared to Type I. Then, varying d<i>V</i>/d<i>t</i> could produce an obvious change...
<p><b>A,</b> Three different action potentials during the rising phase. Vertical arrows depict the p...
<p>(A)-(C) summarize the results produced by varying β<sub>m</sub>. The minimal model exhibits Type ...
<p>Illustrated here are the dynamic characteristics of the two-excitatory-neuron network in <a href=...
<p>A set of sample spikes from Type I and Type II neuron as d<i>V</i>/d<i>t</i> increases from 0.2mV...
<p>(A) Spike threshold for three types of excitability within a range of d<i>V</i>/d<i>t</i> (from 0...
Dynamic spike threshold plays a critical role in neuronal input-output relations. In many neu-rons, ...
Dynamic spike threshold plays a critical role in neuronal input-output relations. In many neurons, t...
<p>(A) Type I excitability is generated through a SNIC bifurcation. Before stimulation, there are th...
<p>(A) Activation curves and kinetics of ionic currents for each cell type. There are three ionic cu...
<p>(A) Phase planes show the fast activation variable <i>V</i> plotted against the slower recovery v...
<p><b>(A)</b> We performed patch-clamp recordings in layer 2/3 pyramidal neurons in vitro, in respon...
<p>The responses and relevant phase plane geometries for Type I and Type II neurons to a set of curr...
<p>(A)-(C) summarize the results in the case of varying γ<sub><i>w</i></sub>. The minimal model exhi...
<p>The neuron is stimulated by current ramp <i>I</i><sub>S</sub>, and the ramp slope <i>K</i> is use...
<p><b>A,</b> Three action potentials (clipped) recorded from a TRN neuron are shown with the membran...
<p><b>A,</b> Three different action potentials during the rising phase. Vertical arrows depict the p...
<p>(A)-(C) summarize the results produced by varying β<sub>m</sub>. The minimal model exhibits Type ...
<p>Illustrated here are the dynamic characteristics of the two-excitatory-neuron network in <a href=...
<p>A set of sample spikes from Type I and Type II neuron as d<i>V</i>/d<i>t</i> increases from 0.2mV...
<p>(A) Spike threshold for three types of excitability within a range of d<i>V</i>/d<i>t</i> (from 0...
Dynamic spike threshold plays a critical role in neuronal input-output relations. In many neu-rons, ...
Dynamic spike threshold plays a critical role in neuronal input-output relations. In many neurons, t...
<p>(A) Type I excitability is generated through a SNIC bifurcation. Before stimulation, there are th...
<p>(A) Activation curves and kinetics of ionic currents for each cell type. There are three ionic cu...
<p>(A) Phase planes show the fast activation variable <i>V</i> plotted against the slower recovery v...
<p><b>(A)</b> We performed patch-clamp recordings in layer 2/3 pyramidal neurons in vitro, in respon...
<p>The responses and relevant phase plane geometries for Type I and Type II neurons to a set of curr...
<p>(A)-(C) summarize the results in the case of varying γ<sub><i>w</i></sub>. The minimal model exhi...
<p>The neuron is stimulated by current ramp <i>I</i><sub>S</sub>, and the ramp slope <i>K</i> is use...
<p><b>A,</b> Three action potentials (clipped) recorded from a TRN neuron are shown with the membran...
<p><b>A,</b> Three different action potentials during the rising phase. Vertical arrows depict the p...
<p>(A)-(C) summarize the results produced by varying β<sub>m</sub>. The minimal model exhibits Type ...
<p>Illustrated here are the dynamic characteristics of the two-excitatory-neuron network in <a href=...