Therapeutic effect of LVFX on influenza virus-infected mice.

<p>Influenza virus infected mice were produced by the intratracheal administration of influenza virus under anesthesia on day 0. After infection, the mice were treated with LVFX on day 2 after infection by means of an intraperitoneal injection of LVFX. (A) Survival curves for control (n = 3), 100 mg/kg LVFX (not infected, n = 3), PBS (n = 10), 25 mg/kg LVFX (n = 10) and 100 mg/kg LVFX (n = 10) treatment during an influenza virus infection. (B) Weight loss during an influenza virus infection. Each bar represents the mean ± SD. **p<0.01 vs vehicle. Experiment was repeated three times.