The blood metabolome-transcriptome interface.
- Jörg Bartel (757375)
- Jan Krumsiek (127460)
- Katharina Schramm (528479)
- Jerzy Adamski (127482)
- Christian Gieger (87555)
- Christian Herder (44905)
- Maren Carstensen (112706)
- Annette Peters (62601)
- Wolfgang Rathmann (107976)
- Michael Roden (73251)
- Konstantin Strauch (73658)
- Karsten Suhre (67967)
- Gabi Kastenmüller (127487)
- Holger Prokisch (26590)
- Fabian J. Theis (127485)
Publication date
June 2015
DOIAbstract
<p><b>A:</b> Distributions of correlation coefficients for metabolite-mRNA, mRNA-mRNA and metabolite-metabolite associations. <b>B:</b> Number of nodes and edges as a function of the absolute correlation coefficient. Red dotted line represents the correlation cutoff used in this study (0.01 FDR). <b>C:</b> Percentages of blood cell type specific markers contained in the BMTI. <b>D:</b> Visualization of the blood metabolome-transcriptome interface. The correlation network consists of 114 metabolites and 522 transcripts connected by 1109 edges. Edge widths represent correlation strengths.</p
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