<p>Compared to wild-type flies, which have a dorsal wing posture (<b>A</b>), flies with a pan-muscular overexpression of full-length Gemin2 (<i>Mef2-GAL4>Gem2</i><sup><i>FL</i></sup>) present with either droopy (<b>B</b>) or held-up (<b>C</b>) wings. (<b>D</b>) <i>Top</i>, Puparia of flies with a strong mesodermal overexpression of Gemin2 (<i>how-GAL4>Gem2</i><sup><i>FL</i></sup>) and the GAL4 driver control (<i>how-GAL4/+</i>). <i>Bottom</i>, Chart showing that Gemin2 overexpressors (<i>how-GAL4>Gem2</i><sup><i>FL</i></sup>) have a significantly larger puparial axial ratio when compared to controls (<i>how-GAL4/+</i>). The mean is marked by a horizontal line running through the data points and error bars are ± S.E.M. (****p<0.0001; <i>how-...
<p>(A) Control wing of a male fly from the <i>A9-Gal</i> line. Longitudinal (L2 to L5) and cross vei...
<p>(<b>A</b>) Left panel: Compared to the control genotype (<i>Mef2-GAL4/+</i>), pan-muscular overex...
<p>Stereo-microscopical (a, c, e and g) and Optical (b, d, f and h) images, demonstrating severely d...
<p>(<b>A</b>) A double but not a single dose of Gemin3 hypomorph, <i>Gem3</i><sup><i>BART</i></sup>,...
<p>(<b>A</b>) Gemin2 knockdown through the expression of a single RNAi transgene (<i>Gem2-IR<sup>gau...
<p>(A) <i>Top</i>, Puparia of flies with ubiquitous overexpression of hSMN (<i>da-GAL4>hSMN</i>), pa...
<p>(<b>A</b>) Compared to controls (<i>Mef2-GAL4>Dcr-2</i> and <i>Gem3-IR<sup>mun</sup>/+</i>), the ...
<p>(<b>A</b>) Larval muscles of wild-type or mutant flies ubiquitously expressing a GFP-tagged Gemin...
<p>(<b>A</b>) Flies with a pan-neuronal Gemin5 knockdown (<i>elav-GAL4>Dcr-2+Gem5-IR<sup>nan</sup>+G...
<p><i>pnr-Gal4</i> and <i>ap-Gal4</i> imaginal disc drivers were used to drive expression of <i>EGFP...
<p>(A) Normal wing position observed in a Wild type fly (B) Abnormal wing position phenotype (wing h...
<p>A) Genetic rescue of wing position phenotypes with genes involved in poly(A) tail regulation. Per...
The SMN-Gemins complex is composed of Gemins 2-8, Unrip and the survival motor neuron (SMN) protein....
The SMN-Gemins complex is composed of Gemins 2–8, Unrip and the survival motor neu-ron (SMN) protein...
The SMN-Gemins complex is composed of Gemins 2-8, Unrip and the survival motor neuron (SMN) protein....
<p>(A) Control wing of a male fly from the <i>A9-Gal</i> line. Longitudinal (L2 to L5) and cross vei...
<p>(<b>A</b>) Left panel: Compared to the control genotype (<i>Mef2-GAL4/+</i>), pan-muscular overex...
<p>Stereo-microscopical (a, c, e and g) and Optical (b, d, f and h) images, demonstrating severely d...
<p>(<b>A</b>) A double but not a single dose of Gemin3 hypomorph, <i>Gem3</i><sup><i>BART</i></sup>,...
<p>(<b>A</b>) Gemin2 knockdown through the expression of a single RNAi transgene (<i>Gem2-IR<sup>gau...
<p>(A) <i>Top</i>, Puparia of flies with ubiquitous overexpression of hSMN (<i>da-GAL4>hSMN</i>), pa...
<p>(<b>A</b>) Compared to controls (<i>Mef2-GAL4>Dcr-2</i> and <i>Gem3-IR<sup>mun</sup>/+</i>), the ...
<p>(<b>A</b>) Larval muscles of wild-type or mutant flies ubiquitously expressing a GFP-tagged Gemin...
<p>(<b>A</b>) Flies with a pan-neuronal Gemin5 knockdown (<i>elav-GAL4>Dcr-2+Gem5-IR<sup>nan</sup>+G...
<p><i>pnr-Gal4</i> and <i>ap-Gal4</i> imaginal disc drivers were used to drive expression of <i>EGFP...
<p>(A) Normal wing position observed in a Wild type fly (B) Abnormal wing position phenotype (wing h...
<p>A) Genetic rescue of wing position phenotypes with genes involved in poly(A) tail regulation. Per...
The SMN-Gemins complex is composed of Gemins 2-8, Unrip and the survival motor neuron (SMN) protein....
The SMN-Gemins complex is composed of Gemins 2–8, Unrip and the survival motor neu-ron (SMN) protein...
The SMN-Gemins complex is composed of Gemins 2-8, Unrip and the survival motor neuron (SMN) protein....
<p>(A) Control wing of a male fly from the <i>A9-Gal</i> line. Longitudinal (L2 to L5) and cross vei...
<p>(<b>A</b>) Left panel: Compared to the control genotype (<i>Mef2-GAL4/+</i>), pan-muscular overex...
<p>Stereo-microscopical (a, c, e and g) and Optical (b, d, f and h) images, demonstrating severely d...