Lipid lowering by diet does not affect ROS levels within the atherosclerotic aortic arch Female <i>Apoe</i>^<i>-/-</i> mice were first fed Western diet to induce advanced lesions in the aortic arch.

<p>Then, lipids were lowered by switching to chow diet for five days. A control group was maintained on Western diet. <i>(A)</i> Intracellular and extracellular ROS were assessed in the atherosclerotic arch (red). <i>(B)</i> Lipid lowering by diet did not affect intracellular ROS. <i>(C)</i> Lipid lowering by diet did not affect extracellular ROS. NS—non significant. One sample t-test. n = 6 in each group.