Protein F57B10.9 in <i>C</i>. <i>elegans</i> is the orthologue of SPG20 in <i>H</i>. <i>sapiens</i>.

<p>(A) Protein sequence alignment using Clustal omega of F57B10.9 and SPG20. These sequences share 23% identity and 65% similarity. Conserved amino acids are marked in grey, and identical amino acids are marked in black. (B) F57B10.9 has one predicted transcript, and the <i>tm5514</i> deletion mutation spans exons 1 through 6.