Effects of clarithromycin on Nrf2 and HO-1 expression levels and on HO-1 immunoreactivity in irradiated lungs of mice.

<p>(A) Nrf2 and HO-1 expression levels in lungs of control (CTL), radiation only (RT), radiation + clarithromycin (RT+CLA), and clarithromycin only (CLA) animal groups. Densitometry values were normalized to β-actin and data are presented as mean ± SEM (n = 2–6 mice per group). *p<0.05 vs CTL mice; †p<0.05 vs RT mice. (B) Immunostained HO-1 in lung tissue by group. Scale bar = 100 μm.