Effects of clarithromycin on inflammation in irradiated lungs of mice.

<p>(A) TNF-α expression in lungs of control (CTL), radiation only (RT), radiation + clarithromycin (RT + CLA), and clarithromycin only (CLA) animal groups. (B) TNFR1 and TNFR2 expression in lungs of respective groups. (C and D) Acetylated NF-κB p65 and (E) COX-2 expression in lungs of respective groups. Densitometry values were normalized to β-actin and data are presented as mean ± SEM (n = 2–6 mice per group). *<i>p</i><0.05 vs CTL mice; †<i>p</i><0.05 vs RT mice. (F) Immunostained COX-2 in lung tissue by group. Scale bar = 100 μm.