<p>We defined gene families based on the presence of protein domains (PFAM) and tested whether genes of a given gene family are enriched in SVs. Panels A and D shows significantly enriched gene families for deletions and duplications relative to the reference strain PS312 as pooled data (unpolarized analysis). The other panels show the enriched gene families after restricting to perfectly collinear regions and interpreting the SVs as derived events (polarized analysis).</p
Genome-wide association studies (GWAS) have indicated potential to identify heritability of common c...
<p>Gene set enrichment analysis of models with impaired Insulin (a, c) or mitochondrial (b) function...
Structural variants (SVs) are large rearrangements (\u3e50 bp) within the genome that impact gene fu...
<p>(A) Genome browser view depicting the concordant and discordant coverage of the control (blue) an...
<p>We classified genes in deleted and duplicated regions (relative to the reference strain PS312) ba...
<p>This figure describes how regions of rare variants were collapsed together and analysed: • Indivi...
<p>(A) DNA sequence and insertion frequency of the 10 most commonly inserted sequences identified wi...
(A) Volcano plot showing differentially expressed genes (DEGs); red dots represent upregulated genes...
<p>Enrichment of gene families in 901 genes with evidence of expression in the AIC but not in the se...
<p>(A) SE38 group vs. PBS group. S95H_NS, S50H_NS and S96_H_NS belong to SE38 group; S32H_NS, S32H_2...
Bioinformatics involves storing, analyzing and making predictions on massive amounts of protein and ...
<p>Functional enrichment of PFAM and TIFRfam domains in differentially expressed gene clusters.</p
<p>The two samples were isolated with either an established method (S) or a modified method using el...
(A) Gene sets from the GSEA Immune Signatures Database (ImmuneSigDB) were used to interrogate log2FC...
International audienceBackground: Accurate catalogs of structural variants (SVs) in mammalian genome...
Genome-wide association studies (GWAS) have indicated potential to identify heritability of common c...
<p>Gene set enrichment analysis of models with impaired Insulin (a, c) or mitochondrial (b) function...
Structural variants (SVs) are large rearrangements (\u3e50 bp) within the genome that impact gene fu...
<p>(A) Genome browser view depicting the concordant and discordant coverage of the control (blue) an...
<p>We classified genes in deleted and duplicated regions (relative to the reference strain PS312) ba...
<p>This figure describes how regions of rare variants were collapsed together and analysed: • Indivi...
<p>(A) DNA sequence and insertion frequency of the 10 most commonly inserted sequences identified wi...
(A) Volcano plot showing differentially expressed genes (DEGs); red dots represent upregulated genes...
<p>Enrichment of gene families in 901 genes with evidence of expression in the AIC but not in the se...
<p>(A) SE38 group vs. PBS group. S95H_NS, S50H_NS and S96_H_NS belong to SE38 group; S32H_NS, S32H_2...
Bioinformatics involves storing, analyzing and making predictions on massive amounts of protein and ...
<p>Functional enrichment of PFAM and TIFRfam domains in differentially expressed gene clusters.</p
<p>The two samples were isolated with either an established method (S) or a modified method using el...
(A) Gene sets from the GSEA Immune Signatures Database (ImmuneSigDB) were used to interrogate log2FC...
International audienceBackground: Accurate catalogs of structural variants (SVs) in mammalian genome...
Genome-wide association studies (GWAS) have indicated potential to identify heritability of common c...
<p>Gene set enrichment analysis of models with impaired Insulin (a, c) or mitochondrial (b) function...
Structural variants (SVs) are large rearrangements (\u3e50 bp) within the genome that impact gene fu...