The survival curves for METABRIC discovery and validation sets.

<p>The survival curves for each breast cancer subtype are generated using Cox proportional hazards model based on the grade and size of the tumour, patient’s age, number of lymph nodes positive and ER status. Each curve represents the survival probability at a certain time after the diagnosis. Ticks on the curve correspond to the observations of patients who are still alive, while drops indicate the death. The probability curves based on the last 10 observations are plotted in dash. The top row is based on the original subtype labels obtained with the PAM50 list and a single classifier (PAM). Middle and bottom rows are based on the labels obtained by Ensemble Learning using the PAM50 and CM1 lists, respectively.