Enforced expression of human ANGPTL2 increased adipose tissue macrophages and promoted M1 macrophage polarization in adipose tissue from db/db mice.

<p>A, Stromal vascular fraction (SVF) was isolated from the epididymal fat pad then stained with F4/80, CD11b, and CD11c antibodies and analyzed by FACS. B, Adipose tissue macrophage number was determined as F4/80+ and CD11b+ fraction and determined by FACS (n = 7–8). Data are mean ± SEM, **: P<0.01, *: P<0.05 compared with LacZ group.