Neutrophil depletion significantly attenuates placental ischemia-induced increase in mean arterial pressure (MAP).

<p>Animals were treated with normal rabbit serum (Control) or antiPMN antibody from 13.5–18.5 dpc. The increase in MAP in RUPP Control (n = 14) compared to Sham Control (n = 5) was significantly inhibited by neutrophil depletion (RUPP antiPMN, n = 9). MAP did not differ between Sham antiPMN (n = 5) and Sham Control groups. Values represent mean ± SE of MAP measured 19.5 dpc. *p<0.05 for indicated comparison.