Phylogenetic and sequence analysis of genogroup (G) II noroviruses (NoVs).

<p>(A), Phylogenetic tree of GII NoVs that is re-drawn according to [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005025#ppat.1005025.ref052" target="_blank">52</a>]. The unique genetic branch consisting of GII.13 and GII.21 genotypes is indicated by a green frame. (B), P domain sequence alignment of NoVs representing each of the 20 GII genotypes with a focus on the residues at the HBGA binding interface. The conserved amino acids constituting the GII conventional HBGA binding interface are indicated with colored letter in frames. The GenBank accession numbers of the P domain sequences are: AY038600.3 (VA387), U07611 (Hawaii), AY134748 (SMV), U22498 (Mexico), X86557 (Lordsdale), AF397156 (MOH), AF414407 (Florida269), AJ277608 (Leeds), AF195848 (Amsterdam), AAK84676 (VA207), AF427118 (Erfurt), AB074893 (SW918), AJ277618 (Wortley), AY113106 (Fayettevil), AY130761 (M7), AY130762 (J23), AY502010 (Tiffin), AY502009 (CS-E1), AY823304 (SW101), AY823306 (SW170), EU373815 (Lucken), AY675554 (OIF), and AB083780.1 (YURI).