Echocardiographic and morphometric analysis of NAGLU^-/- mice.

<p><b>A</b>. Cumulative data of % fractional shortening (FS%) of WT and NAGLU^-/- mice from 16 weeks to 32 weeks of age (*p<0.05). <b>B</b>. Representative M-mode echocardiographic tracings of WT and NAGLU^-/- mice at 16 weeks and 32 weeks of age. <b>C</b>. Cumulative data of mitral annulus dimension (mm) of WT and NAGLU^-/- mice from 16 weeks to 32 weeks of age (*p<0.05). <b>D</b>. Doppler analysis of mitral valve regurgitation of WT and NAGLU^-/- mice at 32 weeks of age. <b>E</b>. Bar graphs showing mitral inflow E-wave to A-wave ratio in WT and NAGLU^-/- mice at 32 weeks of age (*p<0.05). <b>F</b>. Bar graphs showing left ventricle weight to body weight ratio (LVW/BW) in WT and NAGLU^-/- mice at 32 weeks of age (*p<0.05). <b>G</b>. Representative gross morphology of whole hearts from 32-week-old WT and NAGLU^-/- mice.