CNP temporarily inhibited the meiotic resumption of goat oocytes cultured <i>in vitro</i>.

<p>COCs were cultured in medium containing different concentrations (0, 50, 100 and 150 ng/mL) of CNP, and the proportion of oocytes with GV was evaluated after 0, 4, 6, 8 hours of culture, respectively. CNP: C-type natriuretic peptide; COCs: cumulus oocyte complexes; GV: germinal vesicle.