<p>See legend to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132150#pone.0132150.g003" target="_blank">Fig 3</a> for details.</p
<p><b>Copyright information:</b></p><p>Taken from "Design considerations in a sib-pair study of link...
For many inherited diseases, the same mutation is not always expressed in all persons who carry it, ...
AbstractFor many inherited diseases, the same mutation is not always expressed in all persons who ca...
<p>See legend to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132150#pone....
<p>The distribution of the log<sub>10</sub> odds ratio (log<sub>10</sub>OR) is depicted for prevalen...
<p>Prevalence 0.1%-1.0% (A,D), 1%-5% (B,E) or 10–20% (C,F); multiplicative model with γ = 0.1 (A,B,C...
<p>OR: odds ratio</p><p>Proportion of epidemiologically protective mutations at two unlinked loci un...
<p>IQR: inter-quartile range</p><p>Spectrum of causative mutations at two unlinked loci under two di...
<p>We assume the pleiotropic limit and a mutational target size of 1 Mb (see Sections 3.3 and 6.1 in...
Many binary phenotypes do not follow a classical Mendelian inheritance pattern. Interaction between ...
Complex diseases are often highly heritable. However, for many complex traits only a small proportio...
grantor: University of TorontoAn important factor in genetic linkage analysis is the penet...
<p>(LL-BMD) = lower limb BMD, (UL-BMD) = upper limb BMD, (SK-BMD) = skull BMD, (GENE) = closest gene...
Some individuals with a particular disease-causing mutation or genotype fail to express most if not ...
Complex diseases are often highly heritable. However, for many complex traits only a small proportio...
<p><b>Copyright information:</b></p><p>Taken from "Design considerations in a sib-pair study of link...
For many inherited diseases, the same mutation is not always expressed in all persons who carry it, ...
AbstractFor many inherited diseases, the same mutation is not always expressed in all persons who ca...
<p>See legend to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132150#pone....
<p>The distribution of the log<sub>10</sub> odds ratio (log<sub>10</sub>OR) is depicted for prevalen...
<p>Prevalence 0.1%-1.0% (A,D), 1%-5% (B,E) or 10–20% (C,F); multiplicative model with γ = 0.1 (A,B,C...
<p>OR: odds ratio</p><p>Proportion of epidemiologically protective mutations at two unlinked loci un...
<p>IQR: inter-quartile range</p><p>Spectrum of causative mutations at two unlinked loci under two di...
<p>We assume the pleiotropic limit and a mutational target size of 1 Mb (see Sections 3.3 and 6.1 in...
Many binary phenotypes do not follow a classical Mendelian inheritance pattern. Interaction between ...
Complex diseases are often highly heritable. However, for many complex traits only a small proportio...
grantor: University of TorontoAn important factor in genetic linkage analysis is the penet...
<p>(LL-BMD) = lower limb BMD, (UL-BMD) = upper limb BMD, (SK-BMD) = skull BMD, (GENE) = closest gene...
Some individuals with a particular disease-causing mutation or genotype fail to express most if not ...
Complex diseases are often highly heritable. However, for many complex traits only a small proportio...
<p><b>Copyright information:</b></p><p>Taken from "Design considerations in a sib-pair study of link...
For many inherited diseases, the same mutation is not always expressed in all persons who carry it, ...
AbstractFor many inherited diseases, the same mutation is not always expressed in all persons who ca...