<p>Volume changes are shown for control sheep (A, C, E, G) and Batten disease affected sheep (B, D, F, H) in sagittal (A, B)), horizontal (C, D) and two coronal planes (E-H), one at the level of the striatum (E, F), the other at the level of the thalamus (G,H). Scale bar in G is 1cm and the colour scale indicates volume change as ml/year.</p
<p>(<b>A</b>) Section of midbrain at the level of the superior colliculus from sheep 050 with multif...
<p>Dots represent data points for individual sheep, lines show mean ± SEM. n = 10, *P<0.05 compared ...
The density of animals in stables constitutes an essential risk factor in the scale of their affecte...
<p>(A) Mean (± SEM) body weight of control (blue) and Batten disease affected sheep (red) from birth...
<p>Coronal sections are pseudocoloured to show changes in grey matter (A), or white matter (B). The ...
Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN...
Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN...
<p><b>A</b>) vessels per mm<sup>2</sup> airway wall <b>B</b>) mean blood vessel size (µm<sup>2</sup>...
<div><p>Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutation...
The neuronal ceroid-lipofuscinoses (NCLs; Batten disease) are a group of fatal neurodegenerative lys...
International audienceNeuronal ceroid lipofuscinoses (Batten disease) are a group of inherited lysos...
Standard stereotaxic reference systems play a key role in human brain studies. Stereotaxic coordinat...
Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN...
Remerciements : INRA, UMR PRC, Plateforme CIRE, 37380 Nouzilly, Centre Val de LoireThe sheep model w...
Recent progress in gene therapy for CLN5 and CLN6 ovine Batten disease (neuronal ceroid-lipofuscino...
<p>(<b>A</b>) Section of midbrain at the level of the superior colliculus from sheep 050 with multif...
<p>Dots represent data points for individual sheep, lines show mean ± SEM. n = 10, *P<0.05 compared ...
The density of animals in stables constitutes an essential risk factor in the scale of their affecte...
<p>(A) Mean (± SEM) body weight of control (blue) and Batten disease affected sheep (red) from birth...
<p>Coronal sections are pseudocoloured to show changes in grey matter (A), or white matter (B). The ...
Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN...
Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN...
<p><b>A</b>) vessels per mm<sup>2</sup> airway wall <b>B</b>) mean blood vessel size (µm<sup>2</sup>...
<div><p>Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutation...
The neuronal ceroid-lipofuscinoses (NCLs; Batten disease) are a group of fatal neurodegenerative lys...
International audienceNeuronal ceroid lipofuscinoses (Batten disease) are a group of inherited lysos...
Standard stereotaxic reference systems play a key role in human brain studies. Stereotaxic coordinat...
Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN...
Remerciements : INRA, UMR PRC, Plateforme CIRE, 37380 Nouzilly, Centre Val de LoireThe sheep model w...
Recent progress in gene therapy for CLN5 and CLN6 ovine Batten disease (neuronal ceroid-lipofuscino...
<p>(<b>A</b>) Section of midbrain at the level of the superior colliculus from sheep 050 with multif...
<p>Dots represent data points for individual sheep, lines show mean ± SEM. n = 10, *P<0.05 compared ...
The density of animals in stables constitutes an essential risk factor in the scale of their affecte...