Distributions of proteins identified in BHK-21 cells infected with FMDV and proteome-wide accurate quantitation and significance.

<p>(A) The left (black red color) represents up-regulated host proteins in virus-infected cells. The right (green color) represents down-regulated host proteins based on significance B ≤ 0.05. The other parts represent unchanged proteins in FMDV-infected cells. (B) Signal intensities (log10) of all quantified proteins in the FMDV-infected cells are shown as functions of their fold change (log2). The spread of the cloud is lower at high abundance, indicating that quantification is more precise. The criterion of being identified as a significantly regulated protein can be evaluated by the significance B level indicated in blue, red, purple, and green.