Non-linear FRC measurement bias due to decreased pre-capillary dead space.

<p>Bland Altmann plot of functional residual capacity (FRC) determined at lower pre-capillary dead space setting (19 mL instead of 24 mL) minus baseline FRC versus mean of both FRC. Black circles represent children with CF, grey circles former preterm and open circles healthy children. Solid line represent mean difference (0.45%), dotted lines represent upper (0.71%) and lower (0.18%) limits of agreement.