Combinations of peptide 1018 and CHX increased the anti-biofilm killing activity compared to each agent when used separately.

<p>(A) 3D Confocal microscopy images of 3-day-old plaque biofilms on HA and sHA surfaces treated with the combination of peptide 1018 and 2% CHX. The scale bar represents 100 μm. (B) The proportion of dead bacterial cells after treatment with peptide 1018, CHX or the combination of both agents. (C) Total biovolume of biofilm after treatments by peptide, CHX, and their combination.