Additional file 1: of In vivo analysis of Nef’s role in HIV-1 replication, systemic T cell activation and CD4+ T cell loss

Figure S1. Viral loads plotted for individual mice (A). The viral loads for each of the six BLT humanized mice infected with JRCSF from Figure 2A are plotted separately. (B) The viral loads for the six BLT humanized mice infected with JRCSFNefdd from Figure 2A are presented as individual plots. JRCSF infected mice are from four different cohorts and JRCSFNefdd infected mice are from five different cohorts. The cohorts were distributed as follows. Cohort 1—JRCSF 3, 4 and JRCSFNefdd 4,5; Cohort 2—JRCSF 2, and JRCSFNefdd 3; Cohort 3—JRCSF 1; Cohort 4—JRCSF 5, 6 and JRCSFNefdd 6; Cohort 5—JRCSFNefdd 2; Cohort 6—JRCSFNefdd 1