ROC of TLCRR and serum NSE for prediction of unfavorable histopathology.

<p>Receiver-operating-characteristic (ROC) is given for TLCRR (dashed line) and serum NSE (continuous line). AUC-ROC was 0.86 for TLCRR. Optimal cut-off determined by the Youden index was 2.0 (*), resulting in a sensitivity of 68% and a specificity of 100%. AUC-ROC was 0.81 for serum NSE. Optimal cut-off was 25.8 ng/ml (**) with a sensitivity of 74% and a specificity of 85%. AUC-ROC = area under the receiver-operating-characteristic, TLCRR = tumor-to-liver count-rate ratio, NSE = neuron-specific enolase.