Aberrant follicle development in mice with conditional <i>Rb1</i> inactivation in oocytes.

<p>(A) Representative images of hematoxylin and eosin (H&E) stained cross-sections of ovaries from PD 7 control and <i>Rb1-cKO</i> females. (B) Quantitative comparison of the number of primary and secondary follicles at PD 7. (C) Representative images for H&E stained cross-sections from PD 14 control and <i>Rb1-cKO</i> ovaries. (D) Quantitative comparison of the number of secondary/preantral and antral follicles at PD 14. (E) Representative images of H&E stained cross-sections from PD 21 control and <i>Rb1-cKO</i> ovaries. (F) Quantitative comparison of the number of preantral and antral follicles at PD 21. (G) Representative images of H&E stained cross-sections from PD 35 control and <i>Rb1-cKO</i> ovaries. (H and I) Quantitative comparison of the number of antral follicles (H) and corpora lutea (CL; panel I). Data are mean±SEM of for at least 3 mice per group. Scale bars = 20μm for A, and 50μm for B, C, and D.