<p>A single dose of 10 nM siGAPDH depressed mRNA expression for one week, with maximal silencing of 80% observed 24–60 hours post-transfection. Error bars represent s.d. (n = 3).</p
<p>HeLa cells were transfected with the indicated plasmids and after 20 h they were treated with 10 ...
These data are related to our paper “GAPDH-targeted therapy – a new approach for secondary damage af...
<p>A, Total RNA extracted from control siRNA (siCTL) and GAPDH siRNA transfected cells was analyzed ...
<p>Caco-2 monolayer barrier function as measured by TEER was not affected by LNP mediated gene silen...
<p><b>A)</b> LNPs 306O<sub>13</sub> and 303O<sub>13</sub> mediated ~90% silencing at an siRNA dose o...
<p><b>a)</b> α-tubulin was used as a loading control and blot shows chemiluminescence signal from a ...
<p>All LNPs were incubated with cells for 24 hours prior to measuring viability with an MTT assay. E...
<p>siRNA, nkRNA and PnkRNA directed against human (h)GAPDH significantly inhibited GAPDH gene expres...
<p>(<b>A</b>) Concentrated Hs738 CM prepared by culturing with or without 10 μM MEK inhibitor I was ...
<p><b>(A)</b> U87-MG cells treated with the indicated compounds were analyzed by immunoblot for GRP7...
<p>(<i>A</i>) Representative fluorescent images of GAPDH-HT 21 h after labeling with TMR-HT ligand i...
<p>The U937 cells were treated with 100 nM BaP, 100 nM NPh, and 100 nM Phe for seven days. The mRNA ...
AbstractGlyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a classic glycolytic enzyme, and accumul...
<p>Numbering of nkRNA is shown in (A). Inhibition of human GAPDH mRNA expression in HCT 116 cells by...
A, strategy used to construct the iGAPDH2 strain, which contained an anhydrotetracycline (ATc) regul...
<p>HeLa cells were transfected with the indicated plasmids and after 20 h they were treated with 10 ...
These data are related to our paper “GAPDH-targeted therapy – a new approach for secondary damage af...
<p>A, Total RNA extracted from control siRNA (siCTL) and GAPDH siRNA transfected cells was analyzed ...
<p>Caco-2 monolayer barrier function as measured by TEER was not affected by LNP mediated gene silen...
<p><b>A)</b> LNPs 306O<sub>13</sub> and 303O<sub>13</sub> mediated ~90% silencing at an siRNA dose o...
<p><b>a)</b> α-tubulin was used as a loading control and blot shows chemiluminescence signal from a ...
<p>All LNPs were incubated with cells for 24 hours prior to measuring viability with an MTT assay. E...
<p>siRNA, nkRNA and PnkRNA directed against human (h)GAPDH significantly inhibited GAPDH gene expres...
<p>(<b>A</b>) Concentrated Hs738 CM prepared by culturing with or without 10 μM MEK inhibitor I was ...
<p><b>(A)</b> U87-MG cells treated with the indicated compounds were analyzed by immunoblot for GRP7...
<p>(<i>A</i>) Representative fluorescent images of GAPDH-HT 21 h after labeling with TMR-HT ligand i...
<p>The U937 cells were treated with 100 nM BaP, 100 nM NPh, and 100 nM Phe for seven days. The mRNA ...
AbstractGlyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a classic glycolytic enzyme, and accumul...
<p>Numbering of nkRNA is shown in (A). Inhibition of human GAPDH mRNA expression in HCT 116 cells by...
A, strategy used to construct the iGAPDH2 strain, which contained an anhydrotetracycline (ATc) regul...
<p>HeLa cells were transfected with the indicated plasmids and after 20 h they were treated with 10 ...
These data are related to our paper “GAPDH-targeted therapy – a new approach for secondary damage af...
<p>A, Total RNA extracted from control siRNA (siCTL) and GAPDH siRNA transfected cells was analyzed ...
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