Associations between clinical and immunological analytes, after accounting for the effects of age, sex, and CMV status.

<p>Initially, associations were limited to the strongest 0.5% of the cross-assay associations, as defined by smallest p-values. The 3 Luminex assays were considered a single assay. We then looked for analytes having the largest numbers of associations, hereafter called connections. The diagram includes all analytes connected to at least 7 other analytes (n = 9), and the analytes to which these analytes are connected, for a total of 61 analytes. Node size is proportional to the number of connections. Solid lines represent positive correlation, dotted lines negative. Line width is proportional to absolute magnitude of correlation, with thicker lines representing stronger correlations. Line color differs for each of the 9 highly connected analytes.