Iridoids and phenylethanoid from <i>Pedicularis kerneri</i> Dalla Torre growing in Dolomites, Italy

<div><p>In this study, we report the first phytochemical analysis of polar fraction of <i>Pedicularis kerneri</i> Dalla Torre growing in Dolomites, Italy. Several iridoid glucosides were isolated, namely aucubin (<b>1</b>), monomelittoside (<b>2</b>), plantarenaloside (<b>3</b>), euphroside (<b>4</b>), mussaenosidic acid (<b>5</b>) and 8-epiloganic acid (<b>6</b>), showing a composition in accordance with previous study on this genus. The studied samples, collected from Dolomites, presented a chemotype already recognised in species from North America, characterised by euphroside (<b>4</b>) and aucubin (<b>1</b>) as main components, but the main character was the presence of monomelittoside (<b>2</b>) never reported in this genus. The identification of verbascoside (<b>7</b>), leucosceptoside A (<b>9</b>) and echinacoside (<b>10</b>) complete the systematic framing of this species since is ascertained the co-occurrence of phenylethanoid glycosides with iridoids in Lamiales species.</p>