Time course of degradation of selected proteins of interest during wt HSV-1 infection.

<p>HFs were infected with wt HSV-1 (MOI 10) then samples harvested at 3, 6 and 10 h after infection were analyzed by western blot for the indicated proteins. For ZBTB4, the asterisk marks a potentially sumoylated species that decreases in abundance during infection. The panels on the lower right of the figure show the analysis of selected viral proteins in these samples.