Decreased proliferation in cancer cells treated with TM5275 and TM5441.

<p>Representative fluorescence-activated cell sorting (FACS) plots are shown in the upper panels with BrdU positive cells (purple) shown within the upper gate. The mean percentage (± SD) of HT1080 and HCT116 BrdU positive cells after treatment with DMSO (white bar), TM5275 (black bar) or TM5441 (red bar) was graphed, n = 3. * indicates <i>P</i> values compared to DMSO controls < 0.05, ** indicates <i>P</i> < 0.01, and *** indicates <i>P</i> < 0.001.