<p>Genes whose mRNA expression was upregulated or down-regulated in microglia but not astrocytes were graphed according to their average fold increase in microglia. This data is only a partial list of genes and the full set of genes is shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0127336#pone.0127336.s001" target="_blank">S1 Fig</a>. Data for astrocytes are also shown. Data are the mean fold increase relative to mock-infected samples for each cell type. n = 6 for each group including mock groups. Green bars indicate the relative increase over the range of all upregulated genes with a high value of 17.2 (Marco) and a low value of -8.90 (Rgs2). Gene that are cytokines or chemokines are shaded, while genes tha...
The activation of astrocytes and microglia is often associated with diseases of the central nervous ...
Gene network A) microglia. Blue: Down regulation in control samples red: Up regulation marked in red...
Genome-wide expression profiling technology has resulted in detailed transcriptome data for a wide r...
<p>Genes with mRNA that were upregulated or down-regulated in both microglia and astrocytes by at le...
<p>(a) Spider graph representation of component B genes after filtering. Up-regulation of genes in a...
<p>The number of genes significantly (A) induced or (B) down-regulated at 6 hours post stimulation (...
<p>Gene expression levels are expressed as fold change relative to the untreated control (n = 3).</p...
<p>mRNA levels of IL-1β, TNF-α, IL-6 and CCL2 were determined by real-time PCR in microglia (A, C, E...
<p>The fold-change of the genes was relative to their expression in WM. Those genes with a negative ...
<p>(A) Heatmap of top 63 differentially regulated genes among the M1-skewed (LPS), M2a-skewed (IL-4)...
A) Volcano plots displaying differential gene expression analysis of oligodendrocytes (top-left), OP...
<p>The enrichment plots of the immunologic gene expression signatures of activated microglia are sep...
<p>RNA samples from mock, TLR7 or TLR9-stimulated microglia or astrocytes were analyzed at 6 hps for...
<p>Shown are the number of differentially expressed genes and the average fold changes of regulated ...
Astrocytes, the most abundant glial cell population in the central nervous system, have important fu...
The activation of astrocytes and microglia is often associated with diseases of the central nervous ...
Gene network A) microglia. Blue: Down regulation in control samples red: Up regulation marked in red...
Genome-wide expression profiling technology has resulted in detailed transcriptome data for a wide r...
<p>Genes with mRNA that were upregulated or down-regulated in both microglia and astrocytes by at le...
<p>(a) Spider graph representation of component B genes after filtering. Up-regulation of genes in a...
<p>The number of genes significantly (A) induced or (B) down-regulated at 6 hours post stimulation (...
<p>Gene expression levels are expressed as fold change relative to the untreated control (n = 3).</p...
<p>mRNA levels of IL-1β, TNF-α, IL-6 and CCL2 were determined by real-time PCR in microglia (A, C, E...
<p>The fold-change of the genes was relative to their expression in WM. Those genes with a negative ...
<p>(A) Heatmap of top 63 differentially regulated genes among the M1-skewed (LPS), M2a-skewed (IL-4)...
A) Volcano plots displaying differential gene expression analysis of oligodendrocytes (top-left), OP...
<p>The enrichment plots of the immunologic gene expression signatures of activated microglia are sep...
<p>RNA samples from mock, TLR7 or TLR9-stimulated microglia or astrocytes were analyzed at 6 hps for...
<p>Shown are the number of differentially expressed genes and the average fold changes of regulated ...
Astrocytes, the most abundant glial cell population in the central nervous system, have important fu...
The activation of astrocytes and microglia is often associated with diseases of the central nervous ...
Gene network A) microglia. Blue: Down regulation in control samples red: Up regulation marked in red...
Genome-wide expression profiling technology has resulted in detailed transcriptome data for a wide r...