<p>Genes with mRNA that were upregulated or down-regulated in both microglia and astrocytes by at least two-fold were graphed according the average increase between both microglia and astrocytes. Data are the mean fold increase relative to mock-infected samples for each cell type. n = 6 for each group including mock groups. Green bars indicate the relative increase and red bars indicate the relative decrease compared to mock over the range of all upregulated genes with a high value of 52.6 (interleukin 6) and a low value of -8.58 (Rasgrp3). Gene that are cytokines or chemokines are shaded, while genes that were chosen for further analysis by real-time PCR are shown in bold. The rank number is shown on the left side of the gene name.</p
<p>Expression profile of the common macrophage marker Itgam (A), M1 specific marker CD86 (B) and M2 ...
<p>Dendrograms of the gene expression patterns for the 636 genes assigned 2 or more stars are shown....
A) Volcano plots displaying differential gene expression analysis of oligodendrocytes (top-left), OP...
<p>Genes whose mRNA expression was upregulated or down-regulated in microglia but not astrocytes wer...
<p>(a) Spider graph representation of component B genes after filtering. Up-regulation of genes in a...
<p>The number of genes significantly (A) induced or (B) down-regulated at 6 hours post stimulation (...
<p>Gene expression levels are expressed as fold change relative to the untreated control (n = 3).</p...
<p>(A) Heatmap of top 63 differentially regulated genes among the M1-skewed (LPS), M2a-skewed (IL-4)...
<p>Identification and ranking of differentially expressed genes (DEGs) from individual studies using...
<p>mRNA levels of IL-1β, TNF-α, IL-6 and CCL2 were determined by real-time PCR in microglia (A, C, E...
<div><p>The activation of astrocytes and microglia is often associated with diseases of the central ...
The activation of astrocytes and microglia is often associated with diseases of the central nervous ...
Left panel: Plot of cell type marker genes detected as altered in AD compared to control samples bas...
<p>The enrichment plots of the immunologic gene expression signatures of activated microglia are sep...
<p>Shown are the number of differentially expressed genes and the average fold changes of regulated ...
<p>Expression profile of the common macrophage marker Itgam (A), M1 specific marker CD86 (B) and M2 ...
<p>Dendrograms of the gene expression patterns for the 636 genes assigned 2 or more stars are shown....
A) Volcano plots displaying differential gene expression analysis of oligodendrocytes (top-left), OP...
<p>Genes whose mRNA expression was upregulated or down-regulated in microglia but not astrocytes wer...
<p>(a) Spider graph representation of component B genes after filtering. Up-regulation of genes in a...
<p>The number of genes significantly (A) induced or (B) down-regulated at 6 hours post stimulation (...
<p>Gene expression levels are expressed as fold change relative to the untreated control (n = 3).</p...
<p>(A) Heatmap of top 63 differentially regulated genes among the M1-skewed (LPS), M2a-skewed (IL-4)...
<p>Identification and ranking of differentially expressed genes (DEGs) from individual studies using...
<p>mRNA levels of IL-1β, TNF-α, IL-6 and CCL2 were determined by real-time PCR in microglia (A, C, E...
<div><p>The activation of astrocytes and microglia is often associated with diseases of the central ...
The activation of astrocytes and microglia is often associated with diseases of the central nervous ...
Left panel: Plot of cell type marker genes detected as altered in AD compared to control samples bas...
<p>The enrichment plots of the immunologic gene expression signatures of activated microglia are sep...
<p>Shown are the number of differentially expressed genes and the average fold changes of regulated ...
<p>Expression profile of the common macrophage marker Itgam (A), M1 specific marker CD86 (B) and M2 ...
<p>Dendrograms of the gene expression patterns for the 636 genes assigned 2 or more stars are shown....
A) Volcano plots displaying differential gene expression analysis of oligodendrocytes (top-left), OP...