Parameters associated with the use of 3 laboratory indices of liver fibrosis calculated on data at the time of the initial liver biopsy prior to interferon-based therapy for differentiating advanced histological liver fibrosis (METAVIR F3–4) from mild to moderate liver fibrosis (METAVIR F0–2) of the liver on initial biopsy (n = 115).

<p>APRI, aspartate aminotransferase-platelet ratio index; AUROC, Area under the ROC curve; PPV, positive predictive value; NPV, negative predictive value.