Inhibitory effect of betaine on the activation of networks by ammonium ions and its dependence on the operation of GABA(A)-receptors.

<p>Cultures 14 DIV. The records of representative cells. All other abbreviations and descriptions as on <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0134145#pone.0134145.g002" target="_blank">Fig 2</a>. <b>(A)</b> Suppression of Ca²⁺-oscillations induced by 8mM NH₄Cl after the application 10 mM of betaine. N = 136. <b>(B</b>) Disappearance of suppressive effect of betaine in the presence of GABA(A)-receptors antagonist bicuculline (10 μM). N = 124. 200 nM of L-glutamate was added before application of NH₄Cl on Fig B.