Influence of treatment with saline or obestatin on serum concentration of interleukin-1β in the course of ischemia/reperfusion-induced acute pancreatitis.

<p>Key: C = control without induction of acute pancreatitis and treated with saline; O = obestatin given i.p. at the dose of 8 nmol/kg/dose twice a day, starting 24 h after induction of acute pancreatitis; NaCl = saline given i.p. twice a day, starting 24 h after induction of acute pancreatitis; AP = ischemia/reperfusion-induced acute pancreatitis. Values are expressed as mean ± SEM. ^aP<0.05 compared to control; ^bP<0.05 compared to NaCl-treated rats after induction of AP at the same time of observation.