Representative morphological features of the pancreas.

<p>Hematoxilin-eosin counterstain. Histological images are presented in two different magnification for each group. In left column, original magnification 100×. In right column, original magnification 200×. (panel A) sham-operated control rats treated with saline; (panel B) rats with ischemia/reperfusion-induced pancreatitis after 1-day reperfusion; (panel C) rats with ischemia/reperfusion-induced pancreatitis after 2-days reperfusion and treated with saline; (panel D) rats with ischemia/reperfusion-induced pancreatitis after 2-days reperfusion and treated with obestatin; (panel E) rats with ischemia/reperfusion-induced pancreatitis after 5-days reperfusion and treated with saline; (panel F) rats with ischemia/reperfusion-induced pancreatitis after 5-days reperfusion and treated with obestatin; (panel G) rats with ischemia/reperfusion-induced pancreatitis after 9-days reperfusion and treated with saline; (panel H) rats with ischemia/reperfusion-induced pancreatitis after 9-days reperfusion and treated with obestatin; (panel I) rats with ischemia/reperfusion-induced pancreatitis after 14-days reperfusion and treated with saline; (panel J) rats with ischemia/reperfusion-induced pancreatitis after 14-days reperfusion and treated with obestatin. Saline or obestatin (8 nmol/kg/dose) were given i.p. twice a day, starting 24 h after induction of acute pancreatitis.