Western blot analysis of IκBα and NF-κB expression and activation in kidney.

<p>A: Expression of phosphorylated (t-p-IκBα) and total IκBα (t-IκBα), cytosolic (c-p50, c-p65) and nuclear p50 and p65 (n-p50, n-p65) in kidney tissue detected by western blotting. B: Density ratio of c-p50 with β-actin and n-p50 with Lamin B1. C: Density ratio of c-p65 with β-actin and n-p65 with Lamin B1 D: Density ratio of p-IκB and t-IκB. IκBα: inhibitor κBα; NF-κB: nuclear factor kappa B, LPS: lipopolysaccharide; PDS: Panaxadiol saponins; Dexa: dexamethasone. Data represent mean ± SEM. ^#P<0.05 vs. control group; *P<0.05 vs. LPS group (n = 3 per group).