Tumor centroid distribution in each age quartile.

<p>A) Spatial point process model with significant clustering of tumor centroids in different parts of the retina as a function of age at diagnosis. The color code indicates the density of tumor centroids relative to the density expected for a completely random spatial distribution of the same number of tumors on the mapped retinal surface. B) Polar plot of tumor centroids in each age quartile with lines connecting multiple tumors within an eye. C) Mapped tumors within each age quartile are superimposed over one another to map the cumulative tumor burden for each quartile. The color code indicates the fraction of the tumors in each age quartile that overlap at a given location.