Longitudinal changes in IOP, RNFLT, and ONH parameters in control eyes and eyes with experimental glaucoma.

<p>Plots of (A) cumulative IOP difference, (B) RNFLT, (C) mean ALCSD, (D) mean RoC, and (E) mean MRW as a function of study time for all monkeys. The legend presented in panel (A) denotes which filled colored circles correspond to each EG eye and is also applicable to panels (B)–(E). Open white circles represent control eyes. (In [A], open white circles represent control IOP data corresponding to the right-most axis). Progressive increases were measured in cumulative IOP difference and mean ALCSD with increasing study duration, whereas progressive decreases were measured in RNFLT, mean RoC, and mean MRW in nearly all EG eyes.