Acu-LFES prevents diabetes-induced muscle fiber cross-sectional area (MCS) decrease.

<p>A representative cross-sectional area of EDL muscle from normal control (control), Acu-LFES treated normal controls (Acu-LFES), diabetes or diabetes/Acu-LFES mice are showed (A). The cryosections of EDL muscle were immunostained with anti-laminin antibody. The First bar graph (B) shows the average size of myofibers determined from six mice x 8 sections/mouse/group (Bars: mean ± s.e.; n = 9/group; * = p<0.05 vs. control and # = p<0.05 vs. diabetes). The frequency distribution of fiber cross-sectional area in control (grey bar), diabetes (open bar) and diabetes/Acu-LFES (black bar) mice is presented as percent fibers/size of fibers (C).