Mean arteriolar diameters after topical application of Ach–Endothelial- dependent evaluation.

<p>Data are shown as changes of average diameter, expressed as mean ± SD and plotted in superimposed symbols. <b>(A)</b> Overall mean arteriolar diameters after topical application of three concentrations of acetylcholine (10⁻⁹, 10⁻⁷ and 10⁻⁵ M) in the 2 treated groups. <b>(B)</b> Endothelial-dependent responses of groups treated with filtered water, concomitantly associated with chows without vitamin E (C), with normal concentration of vitamin E (75U/kg–C/VE) and supplemented concentrations of vitamin E (375U/kg–C/5XVE). <b>(C)</b> Endothelial-dependent responses of groups that had the filtered water substituted by 10% fructose solution, concomitantly associated with chows without vitamin E (F), with normal concentration of vitamin E (75U/kg–F/VE) and supplemented concentrations of vitamin E (375U/kg–F/5XVE). ^<b>+</b>Significantly different in relation to control; ⁺<i>p</i><0.05 [10^-7M] and both control and control with normal concentration of vitamin E; ⁺<i>p</i><0.01 [10^-5M]. ^#Significantly different from fructose-drinking without vitamin E in chow (^#<i>p</i><0.05).